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Heat shock protein-90 dampens and directs signaling stimulated by insulin-like growth factor-1 and insulin
Heat shock protein-90 (Hsp90) buffers cells from genetic mutations and environmental stresses. To test if this capability reflects a normal physiological function of Hsp90 to buffer cellular signals, the effects of Hsp90 inhibition were measured on activation of Akt. Inhibition of Hsp90 with geldana...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1934560/ https://ncbi.nlm.nih.gov/pubmed/15358562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2004.08.026 |
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