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Heat shock proteins in long-lived worms and mice with insulin/insulin-Like signaling mutations

Heat shock proteins (HSPs) have proven to be effective tools for extending invertebrate lifespan, and inC. elegans daf-2 mutants, longevity resulting from loss of insulin / insulin-like signals is at least partly dependent upon elevated HSP expression. In mice, inhibition of the orthologous growth h...

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Détails bibliographiques
Auteur principal: Swindell, William R.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806032/
https://ncbi.nlm.nih.gov/pubmed/20157538
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