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HSP105 INTERACTS WITH GRP78 AND GSK3 AND PROMOTES ER STRESS-INDUCED CASPASE-3 ACTIVATION
Stress of the endoplasmic reticulum (ER stress) is caused by the accumulation of misfolded proteins, which occurs in many neurodegenerative diseases. ER stress can lead to adaptive responses or apoptosis, both of which follow activation of the unfolded protein response (UPR). Heat shock proteins (HS...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212615/ https://ncbi.nlm.nih.gov/pubmed/18083346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2007.10.032 |
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