What Drives Proteins into the Major or Minor Grooves of DNA?

The energetic profiles of a significant number of protein-DNA systems at 20°C reveal that, despite comparable Gibbs free energies, association with the major groove is primarily an enthalpy driven process, whereas binding to the minor groove is characterized by an unfavorable enthalpy that is compen...

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Hlavní autoři: Privalov, Peter L., Dragan, Anatoly I., Crane-Robinson, Colyn, Breslauer, Kenneth J., Remeta, David P., Minetti, Conceição A.S.A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934558/
https://ncbi.nlm.nih.gov/pubmed/17055530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.09.059
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