A New Xenobiotic-Induced Mouse Model of Sclerosing Cholangitis and Biliary Fibrosis

Xenobiotics and drugs may lead to cholangiopathies and biliary fibrosis, but the underlying mechanisms are largely unknown. Therefore, we aimed to characterize the cause and consequences of hepatobiliary injury and biliary fibrosis in 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC)-fed mice as a nov...

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Main Authors: Fickert, Peter, Stöger, Ulrike, Fuchsbichler, Andrea, Moustafa, Tarek, Marschall, Hanns-Ulrich, Weiglein, Andreas H., Tsybrovskyy, Oleksiy, Jaeschke, Hartmut, Zatloukal, Kurt, Denk, Helmut, Trauner, Michael
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2007
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934539/
https://ncbi.nlm.nih.gov/pubmed/17600122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061133
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