A New Xenobiotic-Induced Mouse Model of Sclerosing Cholangitis and Biliary Fibrosis

Xenobiotics and drugs may lead to cholangiopathies and biliary fibrosis, but the underlying mechanisms are largely unknown. Therefore, we aimed to characterize the cause and consequences of hepatobiliary injury and biliary fibrosis in 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC)-fed mice as a nov...

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Autors principals: Fickert, Peter, Stöger, Ulrike, Fuchsbichler, Andrea, Moustafa, Tarek, Marschall, Hanns-Ulrich, Weiglein, Andreas H., Tsybrovskyy, Oleksiy, Jaeschke, Hartmut, Zatloukal, Kurt, Denk, Helmut, Trauner, Michael
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2007
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934539/
https://ncbi.nlm.nih.gov/pubmed/17600122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061133
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