Cell-Specific IRF-3 Responses Protect against West Nile Virus Infection by Interferon-Dependent and -Independent Mechanisms

Interferon regulatory factor (IRF)-3 is a master transcription factor that activates host antiviral defense programs. Although cell culture studies suggest that IRF-3 promotes antiviral control by inducing interferon (IFN)-β, near normal levels of IFN-α and IFN-β were observed in IRF-3(−/−) mice aft...

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Detaylı Bibliyografya
Asıl Yazarlar: Daffis, Stephane, Samuel, Melanie A, Keller, Brian C, Gale, Michael, Diamond, Michael S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2007
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933455/
https://ncbi.nlm.nih.gov/pubmed/17676997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030106
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