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Reconstitution reveals the functional core of mammalian eIF3

Eukaryotic translation initiation factor (eIF)3 is the largest eIF (∼650 kDa), consisting of 10–13 different polypeptide subunits in mammalian cells. To understand the role of each subunit, we successfully reconstituted a human eIF3 complex consisting of 11 subunits that promoted the recruitment of...

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Detalles Bibliográficos
Main Authors: Masutani, Mamiko, Sonenberg, Nahum, Yokoyama, Shigeyuki, Imataka, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933396/
https://ncbi.nlm.nih.gov/pubmed/17581632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601765
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