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Reconstitution reveals the functional core of mammalian eIF3
Eukaryotic translation initiation factor (eIF)3 is the largest eIF (∼650 kDa), consisting of 10–13 different polypeptide subunits in mammalian cells. To understand the role of each subunit, we successfully reconstituted a human eIF3 complex consisting of 11 subunits that promoted the recruitment of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1933396/ https://ncbi.nlm.nih.gov/pubmed/17581632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601765 |
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