DNA Immunization with Plasmids Encoding Fusion and Nucleocapsid Proteins of Bovine Respiratory Syncytial Virus Induces a Strong Cell-Mediated Immunity and Protects Calves against Challenge

Respiratory syncytial viruses (RSV) are one of the most important respiratory pathogens of humans and cattle, and there is currently no safe and effective vaccine prophylaxis. In this study, we designed two codon-optimized plasmids encoding the bovine RSV fusion (F) and nucleocapsid (N) proteins and...

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Main Authors: Boxus, Mathieu, Tignon, Marylène, Roels, Stefan, Toussaint, Jean-François, Walravens, Karl, Benoit, Marie-Ange, Coppe, Philippe, Letesson, Jean-Jacques, Letellier, Carine, Kerkhofs, Pierre
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933320/
https://ncbi.nlm.nih.gov/pubmed/17459933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00502-07
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