DNA Immunization with Plasmids Encoding Fusion and Nucleocapsid Proteins of Bovine Respiratory Syncytial Virus Induces a Strong Cell-Mediated Immunity and Protects Calves against Challenge

Respiratory syncytial viruses (RSV) are one of the most important respiratory pathogens of humans and cattle, and there is currently no safe and effective vaccine prophylaxis. In this study, we designed two codon-optimized plasmids encoding the bovine RSV fusion (F) and nucleocapsid (N) proteins and...

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Bibliografiska uppgifter
Huvudupphovsmän: Boxus, Mathieu, Tignon, Marylène, Roels, Stefan, Toussaint, Jean-François, Walravens, Karl, Benoit, Marie-Ange, Coppe, Philippe, Letesson, Jean-Jacques, Letellier, Carine, Kerkhofs, Pierre
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2007
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933320/
https://ncbi.nlm.nih.gov/pubmed/17459933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00502-07
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