Human Cytomegalovirus UL84 Interacts with an RNA Stem-Loop Sequence Found within the RNA/DNA Hybrid Region of oriLyt

Human cytomegalovirus (HCMV) lytic DNA replication is initiated at the complex cis-acting oriLyt region, which spans nearly 3 kb. DNA synthesis requires six core proteins together with UL84 and IE2. Previously, two essential regions were identified within oriLyt. Essential region I (nucleotides [nt]...

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Hlavní autoři: Colletti, Kelly S., Smallenburg, Kate E., Xu, Yiyang, Pari, Gregory S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933308/
https://ncbi.nlm.nih.gov/pubmed/17459920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00058-07
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