Interaction of HCMV UL84 with C/EBPα transcription factor-binding sites within oriLyt is essential for lytic DNA replication

Human cytomegalovirus (HCMV) lytic DNA replication is initiated at the cis-acting oriLyt region and requires six core replication proteins along with UL84 and IE2. Although UL84 is thought to be the replication initiator protein, little is known about its interaction with oriLyt. We have now perform...

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Bibliographic Details
Main Authors:	Kagele, Dominique, Gao, Yang, Smallenburg, Kate, Pari, Gregory S
Format:	Artigo
Language:	Inglês
Published:	2009
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2740927/ https://ncbi.nlm.nih.gov/pubmed/19631360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.06.035
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Interaction of HCMV UL84 with C/EBPα transcription factor-binding sites within oriLyt is essential for lytic DNA replication

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