Human Monoclonal Antibody AVP-21D9 to Protective Antigen Reduces Dissemination of the Bacillus anthracis Ames Strain from the Lungs in a Rabbit Model

Dutch-belted and New Zealand White rabbits were passively immunized with AVP-21D9, a human monoclonal antibody to protective antigen (PA), at the time of Bacillus anthracis spore challenge using either nasal instillation or aerosol challenge techniques. AVP-21D9 (10 mg/kg) completely protected both...

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Detaylı Bibliyografya
Asıl Yazarlar: Peterson, Johnny W., Comer, Jason E., Baze, Wallace B., Noffsinger, David M., Wenglikowski, Autumn, Walberg, Kristin G., Hardcastle, Jason, Pawlik, Jennifer, Bush, Kathryn, Taormina, Joanna, Moen, Scott, Thomas, John, Chatuev, Bagram M., Sower, Laurie, Chopra, Ashok K., Stanberry, Lawrence R., Sawada, Ritsuko, Scholz, Wolfgang W., Sircar, Jagadish
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2007
Konular:
Microbial Immunity and Vaccines
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932953/
https://ncbi.nlm.nih.gov/pubmed/17452469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00352-07
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