Production of High-Affinity Human Monoclonal Antibody Fab Fragments to the 19-Kilodalton C-Terminal Merozoite Surface Protein 1 of Plasmodium falciparum

A combinatorial immunoglobulin gene library was constructed from peripheral blood lymphocytes of eight patients infected with Plasmodium falciparum and was screened for the production of human monoclonal antibody Fab fragments to the C-terminal 19-kDa fragment of P. falciparum merozoite surface prot...

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Detalhes bibliográficos
Main Authors: Cheng, Xun-Jia, Hayasaka, Hitoshi, Watanabe, Katsuomi, Tao, Yan-Lin, Liu, Jin-Ye, Tsukamoto, Hideo, Horii, Toshihiro, Tanabe, Kazuyuki, Tachibana, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932930/
https://ncbi.nlm.nih.gov/pubmed/17452466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00062-07
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