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Identification of the Biosynthetic Gene Cluster and an Additional Gene for Resistance to the Antituberculosis Drug Capreomycin

Capreomycin (CMN) belongs to the tuberactinomycin family of nonribosomal peptide antibiotics that are essential components of the drug arsenal for the treatment of multidrug-resistant tuberculosis. Members of this antibiotic family target the ribosomes of sensitive bacteria and disrupt the function...

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Detalhes bibliográficos
Main Authors: Felnagle, Elizabeth A., Rondon, Michelle R., Berti, Andrew D., Crosby, Heidi A., Thomas, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932801/
https://ncbi.nlm.nih.gov/pubmed/17496129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00485-07
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