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Effect of Lamivudine on the Plasma and Intracellular Pharmacokinetics of Apricitabine, a Novel Nucleoside Reverse Transcriptase Inhibitor, in Healthy Volunteers

Apricitabine is a novel deoxycytidine analog reverse transcriptase inhibitor. In vitro apricitabine competes with other deoxycytidine analogues for intracellular phosphorylation mediated by deoxycytidine kinase. The topic of this study, the effect of concomitant administration of apricitabine and la...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Holdich, T., Shiveley, L. A., Sawyer, J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932547/
https://ncbi.nlm.nih.gov/pubmed/17242147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01013-06
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