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Inhaled Large Porous Particles of Capreomycin for Treatment of Tuberculosis in a Guinea Pig Model

Capreomycin is used for the treatment of multidrug-resistant tuberculosis (MDR-TB), but it is limited therapeutically by its severe side effects. The objectives of the present studies were (i) to design low-density porous capreomycin sulfate particles for efficient pulmonary delivery to improve loca...

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Detalhes bibliográficos
Main Authors: Garcia-Contreras, L., Fiegel, J., Telko, M. J., Elbert, K., Hawi, A., Thomas, M., VerBerkmoes, J., Germishuizen, W. A., Fourie, P. B., Hickey, A. J., Edwards, D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932523/
https://ncbi.nlm.nih.gov/pubmed/17517845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01164-06
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