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Dry Powder Nitroimidazopyran Antibiotic PA-824 Aerosol for Inhalation

We formulated PA-824, a nitroimidazopyran with promise for the treatment of tuberculosis, for efficient aerosol delivery to the lungs in a dry powder porous particle form. The objectives of this study were to prepare and characterize a particulate form of PA-824, assess the stability of this aerosol...

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Detalles Bibliográficos
Main Authors: Sung, Jean C., Garcia-Contreras, Lucila, VerBerkmoes, Jarod L., Peloquin, Charles A., Elbert, Katharina J., Hickey, Anthony J., Edwards, David A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663128/
https://ncbi.nlm.nih.gov/pubmed/19139288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01389-08
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