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Identification and Characterization of a New Metallo-β-Lactamase, IND-5, from a Clinical Isolate of Chryseobacterium indologenes

A new natural IND-type metallo-β-lactamase variant, IND-5, was identified in a clinical isolate of Chryseobacterium indologenes. IND-5 shared 92.8% and 92.4% amino acid homology with IND-1 and IND-3, respectively. Purified enzyme (pI = 8.8, M(r) = 25,000) was able to hydrolyze penicillins, some narr...

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Detalhes bibliográficos
Main Authors: Perilli, Mariagrazia, Caporale, Bibiana, Celenza, Giuseppe, Pellegrini, Cristina, Docquier, Jean Denis, Mezzatesta, Marilina, Rossolini, Gian Maria, Stefani, Stefania, Amicosante, Gianfranco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932519/
https://ncbi.nlm.nih.gov/pubmed/17470648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00083-07
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