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Genetic variability in CYP3A4 and CYP3A5 in primary liver, gastric and colorectal cancer patients
BACKGROUND: Drug-metabolizing enzymes play a role in chemical carcinogenesis through enzymatic activation of procarcinogens to biologically reactive metabolites. The role of gene polymorphisms of several cytochrome P450 enzymes in digestive cancer risk has been extensively investigated. However, the...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1931602/ https://ncbi.nlm.nih.gov/pubmed/17605821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-118 |
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