Genetic variability in CYP3A4 and CYP3A5 in primary liver, gastric and colorectal cancer patients

BACKGROUND: Drug-metabolizing enzymes play a role in chemical carcinogenesis through enzymatic activation of procarcinogens to biologically reactive metabolites. The role of gene polymorphisms of several cytochrome P450 enzymes in digestive cancer risk has been extensively investigated. However, the...

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Detaylı Bibliyografya
Asıl Yazarlar: Gervasini, Guillermo, García-Martín, Elena, Ladero, José M, Pizarro, Rosa, Sastre, Javier, Martínez, Carmen, García, Monserrat, Diaz-Rubio, Manuel, Agúndez, José AG
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2007
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1931602/
https://ncbi.nlm.nih.gov/pubmed/17605821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-118
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