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Phosphorylation of the Sic1 Inhibitor of B-Type Cyclins in Saccharomyces cerevisiae Is Not Essential but Contributes to Cell Cycle Robustness
In budding yeast, B-type cyclin (Clb)-dependent kinase activity is essential for S phase and mitosis. In newborn G(1) cells, Clb kinase accumulation is blocked, in part because of the Sic1 stoichiometric inhibitor. Previous results strongly suggested that G(1) cyclin-dependent Sic1 phosphorylation,...
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| Formato: | Artigo |
| Idioma: | Inglês |
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Copyright © 2007 by the Genetics Society of America
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1931548/ https://ncbi.nlm.nih.gov/pubmed/17483408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.073494 |
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