Genetic analysis of the relationship between activation loop phosphorylation and cyclin binding in the activation of the Saccharomyces cerevisiae Cdc28p cyclin-dependent kinase.

We showed recently that a screen for mutant CDC28 with improved binding to a defective Cln2p G1 cyclin yielded a spectrum of mutations similar to those yielded by a screen for intragenic suppressors of the requirement for activation loop phosphorylation (T169E suppressors). Recombination among these...

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Bibliographische Detailangaben
Hauptverfasser: Cross, F R, Levine, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2000
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461042/
https://ncbi.nlm.nih.gov/pubmed/10747052
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