Saccharomyces cerevisiae Ime2 phosphorylates Sic1 at multiple PXS/T sites but is insufficient to trigger Sic1 degradation

The initiation of DNA replication in Saccharomyces cerevisiae depends upon the destruction of the Clb–Cdc28 inhibitor Sic1. In proliferating cells Cln–Cdc28 complexes phosphorylate Sic1, which stimulates binding of Sic1 to SCF(Cdc4) and triggers its proteosome mediated destruction. During sporulatio...

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Detaylı Bibliyografya
Asıl Yazarlar: Sedgwick, Chantelle, Rawluk, Matthew, Decesare, James, Raithatha, Sheetal, Wohlschlegel, James, Semchuk, Paul, Ellison, Michael, Yates, John, Stuart, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Portland Press Ltd. 2006
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1570159/
https://ncbi.nlm.nih.gov/pubmed/16776651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060363
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