A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates β-catenin but its zygotic expression is not essential for the regulation of Armadillo
Mutations in the adenomatous polyposis coli gene (which encodes a protein called APC) are associated with the formation of intestinal polyps and colon cancers. To facilitate the functional study of APC we have isolated its Drosophila homolog (D-APC) by screening an expression library with an antibod...
সংরক্ষণ করুন:
| প্রকাশিত: | Proc Natl Acad Sci U S A |
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| প্রধান লেখক: | , , , , , |
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
National Academy of Sciences
1997
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19302/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8990193/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.1.242 |
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