Gene expression variation in Down's syndrome mice allows prioritization of candidate genes

BACKGROUND: Down's syndrome (DS), or trisomy 21, is a complex developmental disorder that exhibits many clinical signs that vary in occurrence and severity among patients. The molecular mechanisms responsible for DS have thus far remained elusive. We argue here that normal variation in gene exp...

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Autores principales: Sultan, Marc, Piccini, Ilaria, Balzereit, Daniela, Herwig, Ralf, Saran, Nidhi G, Lehrach, Hans, Reeves, Roger H, Yaspo, Marie-Laure
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1929163/
https://ncbi.nlm.nih.gov/pubmed/17531092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-5-r91
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