Optimization and clinical validation of a pathogen detection microarray

DNA microarrays used as 'genomic sensors' have great potential in clinical diagnostics. Biases inherent in random PCR-amplification, cross-hybridization effects, and inadequate microarray analysis, however, limit detection sensitivity and specificity. Here, we have studied the relationship...

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Bibliografische gegevens
Hoofdauteurs: Wong, Christopher W, Heng, Charlie Lee Wah, Wan Yee, Leong, Soh, Shirlena WL, Kartasasmita, Cissy B, Simoes, Eric AF, Hibberd, Martin L, Sung, Wing-Kin, Miller, Lance D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1929155/
https://ncbi.nlm.nih.gov/pubmed/17531104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-5-r93
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