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Two-Color Fluorescence Analysis of Individual Virions Determines the Distribution of the Copy Number of Proteins in Herpes Simplex Virus Particles
We present a single virion method to determine absolute distributions of copy number in the protein composition of viruses and apply it to herpes simplex virus type 1. Using two-color coincidence fluorescence spectroscopy, we determine the virion-to-virion variability in copy numbers of fluorescentl...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Biophysical Society
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1929035/ https://ncbi.nlm.nih.gov/pubmed/17513380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.106351 |
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