Efficacy of intravenous itraconazole against experimental pulmonary aspergillosis.

The efficacy of intravenous itraconazole solubilized in hydroxypropyl-beta-cyclodextrin was assessed in a rat model of Aspergillus fumigatus pneumonia. Immunosuppressed rats were infected by intratracheal inoculation of A. fumigatus conidia. Intravenous administration of various doses of itraconazol...

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Autors principals: Miyazaki, H M, Kohno, S, Miyazaki, Y, Mitsutake, K, Tomono, K, Kaku, M, Koga, H, Hara, K
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC192807/
https://ncbi.nlm.nih.gov/pubmed/8109952
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