Efficacy of intravenous itraconazole against experimental pulmonary aspergillosis.

The efficacy of intravenous itraconazole solubilized in hydroxypropyl-beta-cyclodextrin was assessed in a rat model of Aspergillus fumigatus pneumonia. Immunosuppressed rats were infected by intratracheal inoculation of A. fumigatus conidia. Intravenous administration of various doses of itraconazol...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Miyazaki, H M, Kohno, S, Miyazaki, Y, Mitsutake, K, Tomono, K, Kaku, M, Koga, H, Hara, K
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192807/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8109952/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.12.2762
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