Enterohepatic circulation of NY-198, a new difluorinated quinolone, in rats.

Enterohepatic circulation of NY-198 in rats was studied. NY-198 glucuronide in the bile was rapidly hydrolyzed to NY-198 by the intestinal contents. Hydrolyzed and parent NY-198 in the bile were reabsorbed from the intestine. The amount of NY-198 in enterohepatic circulation was 59.8% of that excret...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Saito, A, Nagata, O, Takahara, Y, Okezaki, E, Yamada, T, Ito, Y
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172121/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3348607/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.1.156
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