Enterohepatic circulation of NY-198, a new difluorinated quinolone, in rats.
Enterohepatic circulation of NY-198 in rats was studied. NY-198 glucuronide in the bile was rapidly hydrolyzed to NY-198 by the intestinal contents. Hydrolyzed and parent NY-198 in the bile were reabsorbed from the intestine. The amount of NY-198 in enterohepatic circulation was 59.8% of that excret...
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| Publicat a: | Antimicrob Agents Chemother |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1988
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172121/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3348607/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.1.156 |
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