Enterohepatic circulation of NY-198, a new difluorinated quinolone, in rats.

Enterohepatic circulation of NY-198 in rats was studied. NY-198 glucuronide in the bile was rapidly hydrolyzed to NY-198 by the intestinal contents. Hydrolyzed and parent NY-198 in the bile were reabsorbed from the intestine. The amount of NY-198 in enterohepatic circulation was 59.8% of that excret...

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Bibliografiske detaljer
Main Authors: Saito, A, Nagata, O, Takahara, Y, Okezaki, E, Yamada, T, Ito, Y
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC172121/
https://ncbi.nlm.nih.gov/pubmed/3348607
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