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Biological characterization of cyclothialidine, a new DNA gyrase inhibitor.

Cyclothialidine is a new DNA gyrase inhibitor isolated from Streptomyces filipinensis NR0484. Structurally, it belongs to a new class of natural products containing a unique 12-membered lactone ring that is partly integrated into a pentapeptide chain. Cyclothialidine was found to be one of the most...

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Detalhes bibliográficos
Main Authors: Nakada, N, Shimada, H, Hirata, T, Aoki, Y, Kamiyama, T, Watanabe, J, Arisawa, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC192769/
https://ncbi.nlm.nih.gov/pubmed/8109932
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