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The Structures of Antibiotics Bound to the E site Region of the 50S Ribosomal Subunit of Haloarcula marismortui: 13-deoxytedanolide and Girodazole

Crystal structures of the 50S ribosomal subunit from H. marismortui complexed with two antibiotics have identified new sites at which antibiotics interact with the ribosome and inhibit protein synthesis. 13-deoxytedanolide binds to the E site of the 50S subunit at the same location as the CCA of tRN...

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Hlavní autoři: Schroeder, Susan J., Blaha, Gregor, Tirado-Rives, Julian, Steitz, Thomas A., Moore, Peter B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925262/
https://ncbi.nlm.nih.gov/pubmed/17321546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.01.081
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