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The Structures of Antibiotics Bound to the E site Region of the 50S Ribosomal Subunit of Haloarcula marismortui: 13-deoxytedanolide and Girodazole
Crystal structures of the 50S ribosomal subunit from H. marismortui complexed with two antibiotics have identified new sites at which antibiotics interact with the ribosome and inhibit protein synthesis. 13-deoxytedanolide binds to the E site of the 50S subunit at the same location as the CCA of tRN...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1925262/ https://ncbi.nlm.nih.gov/pubmed/17321546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.01.081 |
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