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Activation mechanisms for the cystic fibrosis transmembrane conductance regulator protein involve direct binding of cAMP
The CFTR [CF (cystic fibrosis) transmembrane conductance regulator] chloride channel is activated by cyclic nucleotide-dependent phosphorylation and ATP binding, but also by non-phosphorylation-dependent mechanisms. Other CFTR functions such as regulation of exocytotic protein secretion are also act...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1925253/ https://ncbi.nlm.nih.gov/pubmed/17381427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061879 |
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