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Population Bottlenecks as a Potential Major Shaping Force of Human Genome Architecture
The modern synthetic view of human evolution proposes that the fixation of novel mutations is driven by the balance among selective advantage, selective disadvantage, and genetic drift. When considering the global architecture of the human genome, the same model can be applied to understanding the r...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1925129/ https://ncbi.nlm.nih.gov/pubmed/17658953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030119 |
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