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Population Bottlenecks as a Potential Major Shaping Force of Human Genome Architecture

The modern synthetic view of human evolution proposes that the fixation of novel mutations is driven by the balance among selective advantage, selective disadvantage, and genetic drift. When considering the global architecture of the human genome, the same model can be applied to understanding the r...

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Detalhes bibliográficos
Main Authors: Gherman, Adrian, Chen, Peter E, Teslovich, Tanya M, Stankiewicz, Pawel, Withers, Marjorie, Kashuk, Carl S, Chakravarti, Aravinda, Lupski, James R, Cutler, David J, Katsanis, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925129/
https://ncbi.nlm.nih.gov/pubmed/17658953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030119
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