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Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk

BACKGROUND: Cytochrome P450 (CYP) enzymes have the potential to affect colorectal cancer (CRC) risk by determining the genotoxic impact of exogenous carcinogens and levels of sex hormones. METHODS: To investigate if common variants of CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1 and CYP19A1 infl...

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Detalhes bibliográficos
Main Authors: Bethke, Lara, Webb, Emily, Sellick, Gabrielle, Rudd, Matthew, Penegar, Stephen, Withey, Laura, Qureshi, Mobshra, Houlston, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925111/
https://ncbi.nlm.nih.gov/pubmed/17615053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-123
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