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The C-terminal domain of T4 RNA ligase 1 confers specificity for tRNA repair
T4 RNA ligase 1 (Rnl1) is a tRNA repair enzyme that thwarts a tRNA-damaging host response to virus infection. The 374-aa Rnl1 protein consists of an N-terminal nucleotidyltransferase domain fused to a unique C-terminal domain composed of 10 α helices. We exploited an in vitro tRNA splicing system to...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1924901/ https://ncbi.nlm.nih.gov/pubmed/17585047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.591807 |
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