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Structure-guided mutational analysis of T4 RNA ligase 1
T4 RNA ligase 1 (Rnl1) is a tRNA repair enzyme that circumvents an RNA-damaging host antiviral response. Whereas the three-step reaction scheme of Rnl1 is well established, the structural basis for catalysis has only recently been appreciated as mutational and crystallographic approaches have conver...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1664725/ https://ncbi.nlm.nih.gov/pubmed/17068206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.271706 |
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