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Cytotoxic Necrotizing Factor 1 Prevents Apoptosis via the Akt/IκB Kinase Pathway: Role of Nuclear Factor-κB and Bcl-2

Cytotoxic necrotizing factor 1 (CNF1) is a protein toxin produced by some pathogenic strains of Escherichia coli that specifically activates Rho, Rac, and Cdc42 GTPases. We previously reported that this toxin prevents the ultraviolet-B–induced apoptosis in epithelial cells, with a mechanism that rem...

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Detalhes bibliográficos
Main Authors: Miraglia, Alessandro Giamboi, Travaglione, Sara, Meschini, Stefania, Falzano, Loredana, Matarrese, Paola, Quaranta, Maria Giovanna, Viora, Marina, Fiorentini, Carla, Fabbri, Alessia
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924812/
https://ncbi.nlm.nih.gov/pubmed/17507655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-10-0910
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