Rac GTPase Instructs Nuclear Factor-κB Activation by Conveying the SCF Complex and IkBα to the Ruffling Membranes

Nuclear factor-κB (NF-κB) is a ubiquitously expressed transcription factor that plays a central role in directing a vast range of cellular functions. Its activation is controlled by the Rac GTPase and relies on the coordinated cooperation of the E3–ligase complex SCF(βTrCP), composed by Skp-1/Cullin...

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Udgivet i:Mol Biol Cell
Main Authors: Boyer, Laurent, Travaglione, Sara, Falzano, Loredana, Gauthier, Nils C., Popoff, Michel R., Lemichez, Emmanuel, Fiorentini, Carla, Fabbri, Alessia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2004
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363090/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14668491/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-05-0301
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