Cytotoxic Necrotizing Factor 1 Enhances Reactive Oxygen Species-Dependent Transcription and Secretion of Proinflammatory Cytokines in Human Uroepithelial Cells

Uropathogenic Escherichia coli strains frequently produce a Rho-activating protein toxin named cytotoxic necrotizing factor type 1 (CNF1). We herein report that CNF1 promotes transcription and release of tumor necrosis factor alpha, gamma interferon, interleukin-6 (IL-6), and IL-8 proinflammatory cy...

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Detalhes bibliográficos
Main Authors: Falzano, Loredana, Quaranta, Maria Giovanna, Travaglione, Sara, Filippini, Perla, Fabbri, Alessia, Viora, Marina, Donelli, Gianfranco, Fiorentini, Carla
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC162030/
https://ncbi.nlm.nih.gov/pubmed/12819113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.7.4178-4181.2003
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