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Multiple Interactions Drive Adaptor-Mediated Recruitment of the Ubiquitin Ligase Rsp5 to Membrane Proteins In Vivo and In Vitro

Recognition of membrane proteins by the Nedd4/Rsp5 ubiquitin ligase family is a critical step in their targeting to the multivesicular body pathway. Some substrates contain “PY” motifs (PPxY), which bind to WW domains in the ligase. Others lack PY motifs and instead rely on adaptors that recruit the...

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Bibliografiset tiedot
Päätekijät: Sullivan, James A., Lewis, Michael J., Nikko, Elina, Pelham, Hugh R.B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Cell Biology 2007
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924809/
https://ncbi.nlm.nih.gov/pubmed/17429078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-01-0011
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