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Cyclin A/Cdk2 complexes regulate activation of Cdk1 and Cdc25 phosphatases in human cells
Mitotic entry, a critical decision point for maintaining genetic stability, is governed by the cyclin B/Cyclin dependent kinase 1 (Cdc2) complex. In Xenopus oocytes and early embryos, accumulation of cyclin B activates Cdk1, which then phosphorylates and activates the positive regulator Cdc25 in an...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1924680/ https://ncbi.nlm.nih.gov/pubmed/14767478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1207446 |
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