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Src phosphorylation of cortactin enhances actin assembly

Src kinase mediates growth factor signaling and causes oncogenic transformation, which includes dramatic changes in the actin cytoskeleton, cell shape, and motility. Cortactin was discovered as a substrate for Src. How phosphorylation of cortactin can enhance actin assembly is unknown. Here, using a...

詳細記述

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書誌詳細
主要な著者: Tehrani, Shandiz, Tomasevic, Nenad, Weed, Scott, Sakowicz, Roman, Cooper, John A.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924558/
https://ncbi.nlm.nih.gov/pubmed/17606906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701077104
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