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Cortactin Has an Essential and Specific Role in Osteoclast Actin Assembly
Osteoclasts are essential for bone dynamics and calcium homeostasis. The cells form a tight seal on the bone surface, onto which they secrete acid and proteases to resorb bone. The seal is associated with a ring of actin filaments. Cortactin, a c-Src substrate known to promote Arp2/3-mediated actin...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1483026/ https://ncbi.nlm.nih.gov/pubmed/16611741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-03-0187 |
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