The molecular chaperone hsp40 regulates the activity of P58(IPK), the cellular inhibitor of PKR

The interferon-induced double-stranded RNA-activated protein kinase, PKR, likely contributes to both the antiviral and the antiproliferative effects of interferon. We previously found that influenza virus avoids the translational inhibitory effects of activated PKR by activating a cellular inhibitor...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Melville, Mark W., Hansen, William J., Freeman, Brian C., Welch, William J., Katze, Michael G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19244/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8990167/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.1.97
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